Treatment of mood lability and explosive rage with minerals and vitamins: two case studies in children.

Kaplan BJ, Crawford SG, Gardner B, Farrelly G.
Journal of Child and Adolescent Psychopharmacology. 2002 Fall;12(3):205-19.

 

ABSTRACT:

A group of scientists at the University of Calgary and the Alberta Children’s Hospital reported the effects of EMPowerplus on 2 medication-free boys with explosive rage and mood disorders (atypical obsessive-compulsive disorder and pervasive developmental delay), using an ABAB (off-on-off-on) study design.

Results: In both cases, symptoms increased when the micronutrient supplement was withdrawn and improved when the supplement was introduced. When taking the supplement, the boys had fewer emotional outbursts, fewer anxious and obsessional thoughts, more positive mood, and better temper control. Improvements were noted on the Conners Parent Rating Scale (CPRS) mood and temper symptoms, Children’s Version Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) obsessive-compulsive symptoms, and Child Behavior Checklist (CBCL) symptoms of aggressive, delinquent, and anxious/depressed behavior, as well as social and attention problems. Neither boy experienced any adverse effects from taking an adult dose of the nutritional supplement. At the time of publication, both boys had been stable on the nutritional supplement for over 2 years.

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